VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Rat

Scientific Name: Rattus norvegicus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae

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Equid alphaherpesvirus 1

Family: Herpesviridae

Receptor: ITGA4

Receptor ITGA4 information

Summary: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_1001 2019.12 10X Genomics Lung Normal 5029 Link
Vthunter_1002 2019.12 10X Genomics Lung Normal 5924 Link
Vthunter_1009 2017.11 Fluidigm C1 UrogenitalSinus Normal 114 Link
Vthunter_110073 2019.12 MARS-seq TotalBrain Normal 2304 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of ITGA4 in human tissues   [NCBI]

Expression: Broad expression in spleen (RPKM 22.7), appendix (RPKM 22.2) and 17 other tissues?

Protein expression of ITGA4 in human tissues   [Proteinatlas]